J'ai suis allée chercher d'autres articles pour continuer nos discussions :
1. Article Japonais
A cross-sectional study of primary biliary cirrhosis in Japan: utilization of clinical data when patients applied to receive public financial aid.
Sakauchi F, Mori M, Zeniya M, Toda G.
Department of Public Health, Sapporo Medical University School of Medicine, Japan.
sakauchi@sapmed.ac.jp
BACKGROUND: There have not been many reports regarding primary biliary cirrhosis (PBC) in Asia. We conducted a cross-sectional study of PBC in Japan. METHODS: In fiscal year 1999, 9,761 patients with symptomatic PBC were registered to receive public financial aid from the Ministry of Health, Labour and Welfare of Japan. For our cross-sectional study we chose 5,805 patients whose clinical data had been written between 1999 and 2000, and statistically analyzed the data, including sex, age, major symptoms, and laboratory data. RESULTS: Our study estimated that the male-to-female ratio was 1:8.0. The median ages of male and female patients were 59 and 60 years, respectively. The major symptoms and physical findings were as follows: pruritus 53.3%, jaundice 11.3%, xanthomas 5.8%, splenomegaly 38.1%, and esophageal varices 19.1%. Antimitochondrial antibody (AMA) was positive in 86.6%, but its positive rate was lower among Japanese patients than among those in western countries. IgM levels were higher among AMA-positive patients than among AMA-negative patients. Regarding Sjogren's syndrome, rheumatoid arthritis, chronic thyroiditis, and scleroderma, patients had lower frequencies of complicated autoimmune diseases than those in western countries. CONCLUSIONS: The male-to-female ratio, frequencies by age group, symptoms and physical findings among patients with PBC were consistent with previous reports in Japan and from other countries. However, positivity of AMA and the frequency of complicated autoimmune diseases were lower among patients in Japan than among those in western countries.
Nous apprenons ainsi qu'au Japon il y a 9 761 patients souffrant d'une CBP avec symptômes.
Si l'on compare avec les données estimées pour l'Europe, c'est moitié moins que chez nous. Ils disent être comparables aux chiffres dans les autres régions, mais .....
Cependant je ne pense pas qu'il y a eu en Europe un vrai recensement des malades. Pour nos amis japonais, tant mieux, mais prennent- ils de la bile d'ours depuis le biberon ?
Ils sont également chanceux d'avoir moins de maladies associées que dans les pays occidentaux.
Il faudrait regarder ce qu'il y a dans leur mode de vie qui motive cette difference, comme c'est le cas par ailleurs des maladies cardio-vasculaires.
2. Article Taiwanais
A child with primary sclerosing cholangitis successfully treated by liver transplantation.
Chen CH, Ho MC, Lee PH, Chang MH, Jeng YM, Ni YH.
Department of Pediatrics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Primary sclerosing cholangitis (PSC) happens mainly in middle-aged men and is seldom diagnosed in children. Childhood PSC undergoing liver transplantation is rarely reported. Here we present a 12-year-old girl who was admitted with a 6-day history of fever, abdominal pain, fatigue, jaundice, and splenomegaly. Liver histological examination revealed the destroyed bile ducts and bridging fibrosis. Endoscopic retrograde cholangiopancreatography (ERCP) showed beaded appearance of right intrahepatic ducts and absent left intrahepatic ducts. PSC was diagnosed. Because of decompensated liver function, she received a living-related orthotopic liver transplantation (OLT). The post-transplantation course was uneventful during the 12-month follow-up. She experienced neither additional episode of cholangitis nor recurrence of liver cirrhosis after OLT.
La CSP est une maladie qui touche surtout une population masculine et díage moyen. Il y a eu le cas díune jeune demoiselle de 12 ans qui a reçu une greffe du foie. Le succès de líopération est très encourageant et après une année de suivi thérapeutique elle ne présente pas de problèmes.
Ceci mía fait penser à notre jeune adhérent (plutôt ses parents qui ont adhéré) de 8 ans qui a été diagnostiqué avec une CSP. Ils níont pas de micro et je ne sais pas bien comment apporter un soutien à ce garçon. Mon envie serait de faire une bande dessinée spéciale de dédramatisation de la maladie et ses symptômes, mais ce níest pas simple. Avez-vous des idées ? Pour soutenir les parents vous pouvez envoyer des messages de sympathie aux parents sur líadresse de líassociation et nous leur transmettrons:
info@albi-pbc.org
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